Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Is hydroxychloroquine immunosuppressant Chloroquine diphosphate salt sigma solubility Plaquenil and neutropenia Chloroquine phosphate dosage in child Discoid lupus erythematosus is the most common type of chronic cutaneous lupus CCLE, an autoimmune skin condition on the lupus erythematosus spectrum of illnesses. It presents with red, inflamed, coin-shaped patches of skin with a scaling and crusty appearance, most often on the scalp, cheeks, and ears. Discoid lupus erythematosus DLE is a form of lupus that mainly affects your skin. DLE is different from systemic lupus erythematosus SLE, the most common form of lupus, which can affect any part of the body. Are You Confident of the Diagnosis? Discoid lupus erythematosus DLE is a form of chronic cutaneous lupus erythematosus CCLE. A diagnosis of discoid lupus erythematosus can be made with the characteristic clinical appearance and location of cutaneous lesions together with histopathologic confirmation. It is a photosensitive dermatosis, but there may not be a clear temporal Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Chloroquine for discoid lupus Early Diagnosis and Treatment of Discoid Lupus Erythematosus American., Discoid Lupus Erythematosus Only Affects Your Skin Plaquenil baseline españolHydroxychloroquine and t cells Chloroquine Aralen Quinacrine Atabrine. Anti-malarials are particularly useful in treating discoid lupus, subacute cutaneous lupus, and mouth sores associated with lupus; they are also effective in treating rheumatoid arthritis and Sjogren’s syndrome. All information contained within the Johns Hopkins Lupus Center website is. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Discoid Lupus Erythematosus DLE, Chronic Discoid Lupus Erythematosus.. Aralen chloroquine Malaria Drug Side Effects & Dosage. Hydroxychloroquine is used to treat discoid lupus erythematosus DLE or systemic lupus erythematosus SLE or lupus. It is also used to treat acute and chronic rheumatoid arthritis. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms Tablet; Before Using Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition. Cutaneous lupus erythematosus CLE is an autoimmune, inflammatory skin disease seen in patients with or without systemic lupus erythematosus SLE. The management of CLE includes treatment and prevention of lesions, as well as routine assessment for systemic disease. Treatment options include both topical and systemic therapies.