As a result, the body produces antibodies that inflict cell damage, most commonly targeting joints, skin, kidneys and the nervous system. I think even though they say it doesn't make a difference, I feel wierd if I don't take my plaquenil sometimes. Hi want2bepainfree, If you don't have to, don't stop your plaquenil. No one knows but I cry sometimes when no one is around to see me. Hugs, Mel Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. Join the group and find support for coping with lupus. I stopped taking the plaquenil the beginning of December. And when I'm crying like a baby--I could feel the pain just throb in me. I took plaquenil for several years, then I went to the Mayo Clinic and they didn't think I had lupus and took me off. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Preparation of chloroquine Is plaquenil toxicity reversible It depends on which ones you're using, but I'll assume it's some form of an SSRI. Personally, I was using effexor. I tapered off quickly, and it was hell. What they don't tell you is that SSRIs often have terrible withdrawals. These are just some. In most cases, if you stop taking your medication cold turkey, you will experience many negative side effects. In this post you will learn more about why you shouldn't stop taking your thyroid medication without physician supervision, the side effects of stopping thyroid medication abruptly, reasons why it isn't safe and what to do instead. If you don't have to, don't stop your plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. It doesn't agree with my stomach (I take it with meals too). The pain in my swollen neck glands is horrific, and my arms and legs are hurting once again. Why does it seem like my whole life just turned for the worst --it was like I was fine one day and the next I'm so ill. It was pure hell, every joint in my body hurt and the fatigue was tremendous. As Tracy stated it is such as slow acting drug when you first start it, it's really hard to tell if it's working, it's not until we stop the med that we realize what a huge difference it was making. I happen to run out of my medication and fail to be in a hurry to get a refill because I had convinced myself that it wasn't working anyway. I missed 2 doses and felt a lot of pain in my arms, and had a pretty bad couple of days. Just wondering if any of you experience any pain if you don't take a few pills. What happens when yoou stop taking hydroxychloroquine abruptly Stopping Plaquenil - General Discussion - Life With Lupus, Side Effects of Stopping Thyroid Medication Abruptly. Plaquenil monitoring guidelines I had no problems taking Hydroxychloriquine for RA as it stopped the flare up in a short time. Stupidly I thought I didn't need it so asked my doc if I could stop. That's when I became inflamed but not the joints until another flare up 11 months later. I think it keep my acute pancreatitis at bay as well as RA. Does anyone know if you have to be weaned off Plaquenil? I've.. Stopping plaquenil. DailyStrength. What Actually Happens to Your Body When You Stop the Keto.. Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision. What happens if I miss a dose Plaquenil, Plaquenil Sulfate, Quineprox? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. However, if you don’t have a history of heart attack or stroke and you want to stop taking statins, your first step should be to talk to your doctor. They can help you find out what your risk.