Hydroxychloroquine cardiotoxicity

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  1. Alexandrx New Member

    Hydroxychloroquine cardiotoxicity


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    Is not known. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. Activity in vitro and in Clinical Infections Hydroxychloroquine is active against the erythrocytic Request PDF Hydroxychloroquine cardiotoxicity in systemic lupus erythematosus A report of 2 cases and review of the literature Background Hydroxychloroquine HCQ is extensively used in the. If cardiotoxicity is suspected, prompt discontinuation of hydroxychloroquine may prevent life-threatening cardiac complications. Renal disease Because renal clearance of hydroxychloroquine does not correlate with creatinine clearance, dosage adjustments are not required in patients with renal impairment.

    However, the exact mechanism of HCQ cardiotoxicity remains unclear and it is difficult to identify risk factors. Abstract: Hydroxychloroquine (HCQ)-induced cardiomyopathy is one of the rare but severe complications following prolonged HCQ use.

    Hydroxychloroquine cardiotoxicity

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Hydroxychloroquine cardiotoxicity in systemic lupus erythematosus A.

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  4. Hydroxychloroquine HCQ, a common anti-rheumatic medication, can be cardiotoxic and cause systolic or diastolic heart failure HF. A 65 year old man presented with acute decompensated HF. He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years.

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    Acute hepatitis, cardiotoxicity, and retinopathy may occur with therapeutic doses. The effects of overdosage with hydroxychloroquine include headache, drowsiness, visual disturbances, convulsions, cardiovascular collapse, and respiratory arrest. Toxic retinopathy has also been associated with higher doses and longer duration of use. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. HCQ cardiotoxicity is uncommon, but as HCQ use and duration of therapy increase, we expect more cases to occur. Further study will be necessary to identify risk factors for this complication and to estimate the relative impact of antimalarial therapy on cardiac disease in SLE patients.

     
  5. art_monster Well-Known Member

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic Hydroxychloroquine Oral Tablet Drug Information, Side Effects. Vitamin d and Hydroxychloroquine sulfate drug interactions.
     
  6. Syerke User

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION Plaquenil Hydroxychloroquine Sulfate Plaquenil Oral Uses, Side Effects, Interactions, Pictures.
     
  7. Sektor New Member

    Do hypnozoites cause relapse in malaria? - ScienceDirect By contrast, a combination of chloroquine and primaquine has mainly been used historically for the treatment of P. vivax malaria. However, resistance to chloroquine now requires partnering of primaquine with other blood schizontocidal agents such as artemisinin, which is effective against P. vivax parasites in the bloodstream 62, 63, 64.

    CHLOROQUINE PHOSPHATE, USP
     
  8. RedZebra Guest

    Hydroxychloroquine Oral Route Side Effects - Mayo Clinic These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about.

    Plaquenil Hydroxychloroquine - Side Effects, Dosage.