It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine pills given to troops in viet name Plaquenil muscle pain User Reviews for Plaquenil to treat Lyme Disease, Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Is it true that Plaquenil stays in your system for months after you discontinue using it? - I took it for a very short time, and I know it damaged my eyes, but everything I read says they have no proof of it hurting a persons eyes in a short amount of time. - Healthboards - Infectious Diseases - Lyme Disease Plaquenil Dec 16, 2008 A 70 year old male patient was diagnosed with Lyme disease 6 or 7 months ago. He reported a history of tick bite and rash in 2002. He received a short course of antibiotics at that time. When I saw him initially he complained of knee pain and swelling, fatigue, generalized arthralgia joint pain, numbness and tingling and an irregular heart beat. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil treatment lyme disease Lyme Disease Treatment & Management Approach Considerations., Healthboards - Infectious Diseases - Lyme Disease Plaquenil Heterocyclic ring present in chloroquine Lori, I'm not medically trained, but here's what I find on the internet for your consideration Plaquenil is a drug used to treat malaria and also in autoimmune conditions such as lupus and rheumatoid arthritis. The references I have found as to using it in Lyme treatment combine Plaquenil with another medication at the same time. ARE YOU TAKING PLAQUINIL? - Lyme Disease - MedHelp. LymeMD Plaquenil alone?. Plaquenil questions -. Jan 17, 2014 User Reviews for Plaquenil to treat Lyme Disease, Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Hi, I have lyme disease and have frequently been on plaquenil only in the summer as stronger drugs are used when I'm not in the sun and I've yet to experience this. But I do know that it is often used to prevent and treat malaria and that many drugs that deal with such things have a tendency to cause some crazy dreams. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Lyme disease and for what kind of people. The study is created by eHealthMe from 7 Plaquenil users and is updated continuously.