According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. Aralen dose Chloroquine tablets nhs Plaquenil tablets prospect A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Drug resistance in malaria Umar Farooq & R. C. Mahajan Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India Ever since the discovery of the first case of chloroquine resistance along the Thai-Combodian border P. falciparum was resistant against chloroquine throughout India but sensitive to mefloquine as echoed by Wangdi et al. 2016. However, in all seven bordering countries, extensive chloroquine drug resistance has been emerged in a high proportion Centers for Disease Control and Prevention, 2017. These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine). Chloroquine resistance india Chloroquine Resistance in Malaria - ResearchGate, Drug resistance in malaria Methylene blue falciparum target chloroquineHydroxychloroquine dose for raPainful muscle spasms from plaquenilPlaquenil maculopathy managementChloroquine resistance mechanism nbme 18 DRUG RESISTANT MALARIA Chloroquine resistance Chloroquine is ineffective in almost all malaria endemic countries In India chloroquine resistance was first detected in 1973 in Assam. Severe in northeast and southeastern regions of India with high morbidity and mortality. DRUG RESISTANT MALARIA CURRENT STATUS. Frontiers Commentary Malaria elimination in India and regional.. Molecular monitoring of antimalarial drug resistance in India Ghosh SK.. Chloroquine phosphate tablets are indicated for the Treatment of uncomplicated malaria due to susceptible strains of P. falciparum, P.malariae, P. ovale, and P.vivax. Prophylaxis of malaria in geographic areas where resistance to Chloroquine is not present. Treatment of extraintestinal amebiasis. India is home to highest number of drug-resistant TB patients. DownToEarth. Down To Earth is a product of our commitment to make changes in the way we manage our environment, protect health and secure livelihoods and economic security for all. In India, 12‐15 million new cases of Plasmodium vivax occur each year. These cases are successfully treated with 600 mg chloroquine adult dose. We report the results of malaria treatment of a 13‐year‐old.