Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Taking plaquenil Chloroquine treatment Hydroxychloroquine may interact with other medications Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance. DRUG INTERACTIONS Digoxin. Concomitant PLAQUENIL and digoxin therapy may result in increased serum digoxin levels serum digoxin levels should be closely monitored in patients receiving combined therapy. Insulin Or Antidiabetic Drugs. As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. What other drugs will affect Plaquenil? Plaquenil can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal medicine; antiviral medicine to treat hepatitis or HIV/AIDS; antidepressants or antipsychotic medicines; For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Interaction of plaquenil with other drugs Hydroxychloroquine, chloroquine and other potential COVID., Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Drug interactions between hydroxychloroquineChloroquine dose during pregnancyLeflunomide hydroxychloroquine combinationAntacid and plaquenilStop hair loss plaquenil Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Plaquenil - Uses, Side Effects, Interactions -. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Oral Route Before Using - Mayo Clinic. The study is based on hydroxychloroquine sulfate and doxycycline hyclate the active ingredients of Plaquenil and Doxycycline hyclate, respectively, and Plaquenil and Doxycycline hyclate the brand names. Other drugs that have the same active ingredients e.g. generic drugs are not considered. Dosage of drugs is not considered in the study. What are the possible side effects of antimalarial drugs? Plaquenil is most often well-tolerated but, like with any drug, side effects are possible. Most people about 90% who take antimalarial medications experience no side effects. If common side effects do occur, they are usually minor and last only for a short period of time. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Side effects, drug interactions, pregnancy safety information, and dosage information should be reviewed prior to taking this medication.