It’s also referred to as knee instability or weak knees. While it’s often accompanied by pain, this isn’t always the case. Plaquenil and low neutrophils Hydroxychloroquine sulphate tablets Plaquenil and Knee joint replacement by duration, gender and age - a study of FDA data Summary Knee joint replacement is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Enbrel, and have Pain. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Dec 01, 2017 Knee buckling is when one or both of your knees give out. It’s also referred to as knee instability or weak knees. While it’s often accompanied by pain, this isn’t always the case. However, if it keeps happening, it could be a sign of something else. If it’s only happened once or twice, you may have just stumbled. Plaquenil knee weakness Plaquenil can cause back and leg pain? What type?, Taking Plaquenil for Rheumatoid Arthritis Hydroxychloroquine drug guidePlaquenil psoriatic arthritisHydroxychloroquine sulfate tablets ipPlaquenil uptodate Jun 25, 2013 Call your doctor at once if you have a serious side effect such as muscle weakness, twitching, or uncontrolled movement; loss of balance or coordination; blurred vision, light sensitivity, seeing halos around lights; pale skin, easy bruising or bleeding; confusion, unusual thoughts or behavior; or seizure convulsions. Hydroxychloroquine - thigh muscle weakness?. Knee Buckling 5 Causes and How to Treat Them. Plaquenil Hydroxychloroquine Sulfate - Sanofi. Plaquenil and Weakness - from FDA reports Summary Weakness is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Osteoporosis. This medication relieved my joint pain, muscle weakness, myositis, pleuritic pain, and fatigue after about 2-3 months of starting the medication. Muscle weakness can be a symptom of many chronic conditions and acute infections. It can also be a side effect of certain medications. Find out more about the causes of muscle weakness here.