Chloroquine pharmacological class

Discussion in 'Canadian Pharmacies' started by akiana-v, 12-Mar-2020.

  1. Clr81 XenForo Moderator

    Chloroquine pharmacological class


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

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    The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial. Oct 04, 2019 Many experts consider chloroquine, when given in usual therapeutic doses to WHO Class II and III G6PD deficient patients, to probably be safe Cappellini 2008; Glader 2017; Luzzatto 2016; Youngster 2010. Safety in Class I G6PD deficiency ie, severe form of the deficiency associated with chronic hemolytic anemia. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen.

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Chloroquine pharmacological class

    Cinnamoylated chloroquine analogues A new structural class of., Chloroquine Professional Patient Advice -

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  3. Chloroquine hydrochloride Injection 50 mg/ml 40 mg/ml base chloroquine phosphate Tablets 250 mg 150-mg base; 500 mg 300-mg base Indications and dosages Suppressive prophylaxis. Adults 500 mg 300-mg base P. O. on same day once weekly beginning 2 weeks before exposure.

    • Chloroquine hydrochloride - GLOWM.
    • Chloroquine Indications, Side Effects, Warnings -.
    • Chloroquine - Wikipedia.

    Chloroquine belongs to a class of drugs known as antimalarials. The United States Centers for Disease Control provide updated guidelines and travel recommendations for the prevention and treatment. Chloroquine is the drug of choice for travel to areas where chloroquine resistance has not been described. Chloroquine is active against the erythrocytic forms Fig. 6.3 of sensitive strains of all species of malaria, and it is also gametocidal against P. vivax, P. malariae, and P. ovale. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your.

     
  4. warhunter User

    500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart. Hydroxychloroquine toxicity - EyeWiki Chloroquine MedlinePlus Drug Information Chloroquine Dosage Guide with Precautions -
     
  5. tashik Moderator

    Plaquenil Side Effects on Your Eyes and Vision The changes are most often permanent, but in some cases, vision has improved. Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. Risk factors include advanced age and having pre-existing retinal disease.

    My Take on New Ocular Screening Guidelines for Plaquenil.