Hydroxychloroquine routine diagnostics

Discussion in 'Canadian Pharmacies' started by Ari_24, 09-Mar-2020.

  1. Olinka New Member

    Hydroxychloroquine routine diagnostics


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Specifically, spectral domain OCT is one of three objective tests now recommended for routine screening of patients on Plaquenil. The other two are multifocal electroretinogram mfERG and fundus autofluorescence FAF. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Hydroxychloroquine is used for its effect on systemic lupus erythematosus SLE disease activity and long-term benefits. This can be limited by adherence. One way to assess adherence is to measure blood levels. Conflicting data exist regarding blood levels and disease activity.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Hydroxychloroquine routine diagnostics

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  5. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD. It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms.

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    If abnormalities are present only unilaterally, investigate other causes besides hydroxychloroquine toxicity see “Differential Diagnosis of Bull’s-Eye Maculopathy”. Mechanism of Toxicity. The mechanism of hydroxychloroquine retinal toxicity has yet to be fully elucidated. These drugs can slow the progression of rheumatoid arthritis and save the joints and other tissues from permanent damage. Common DMARDs include methotrexate Trexall, Otrexup, others, leflunomide Arava, hydroxychloroquine Plaquenil and sulfasalazine Azulfidine. Side effects vary but may include liver damage. QSS Diagnostics is a full service laboratory, offering cutting-edge diagnostic testing within our state-of-the-art facility. Our service offerings range from routine laboratory services to the latest in genetic testing with a focus on high quality customer service, and technology.

     
  6. Andrew2006 Moderator

    Rheumatoid arthritis is a long-term inflammatory condition that can affect the joints and other tissues and organs in the body. Hydroxychloroquine Plaquenil - medications for Rheumatoid. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Rheumatoid Arthritis Drug Guide Types of Drugs, Uses, Side Effects
     
  7. erls Moderator

    Living With One Kidney National Kidney Foundation Most people who are born without a kidney or with only one working kidney lead normal, healthy lives. A person may have had one kidney removed during an operation in order to treat an injury or a disease like cancer. A person may have donated one kidney to a person who needed a kidney transplant. What if I was born with only one "working" kidney?

    Will you have Acute kidney failure with Plaquenil - eHealthMe