I can say that the prednisone wean was successful, even after having only been on plaquenil a few months. To answer some of your other questions, it was the same timeframe for me. Plaquenil to treat ankylosing spondylitis Can plaquenil cause yeast infections Plaquenil knee side effects Most common side effects people have besides Withdrawal syndrome * Drug Ineffective 15 people, 30.00%. Pain 12 people, 24.00%. Nausea And Vomiting 12 people, 24.00%. Feeling Abnormal 11 people, 22.00%. Insomnia sleeplessness 11 people, 22.00%. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. But I couldn't handle the heart issue and not being able to breathe (plus all the other pains). Yesterday would've been my 4th day at the reduced dose. Plaquenil withdrawal side effects Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Plaquenil - Uses, Side Effects, Interactions - Effects of hydroxychloroquine I believe it is like any other drug, side effects can and do happen, but they are very individualized. I would like to be able to keep taking plaquenil, I just want to reduce my dose by half. I had no idea it was going to so profoundly impact me, and I guess I feel like I need to understand why. Let me tell you what weaning down from Plaquenil is like.. Plaquenil Side Effects on Your Eyes and Vision. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Comment Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells.