So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Plaquenil lupus dose Plaquenil ophthalmic side effects Buy plaquenil Hydroxychloroquine generic brands I say this because Plaquenil has a chemical half-life of 30-60 days you can confirm this on wiki or RX info on the drug--so it takes a LONG time to get out of your system.long for you to notice changes in days. If you remember, most wait at least 3 months before they even see any improvement. When the physician looked inside, he saw both pink and peach tablets, some split in half. Initially, the patient had been taking a 20-mg tablet twice daily. When the physician lowered the dose to 10 mg twice daily, the new prescription was filled. Plaquenil, a warning. Hello all, My wife had Lupus and was taking Plaquenil 200mg daily. If you’re having issues with Plaquenil. I literally just spent half the day doing normal girl things with my niece and now I'm lying in bed wanting to just die of pain. I feel like I'm on the verge of a breakdown because I want to feel normal again. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Can you break plaquenil in half PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION, Tablet Splitting—Only If You “Half” To Plaquenil red spotsSulfasalazine and plaquenilPlaquenil what does it do Sometimes what is suggested no antacid for 4 hours is not necessarily required if it means you can't or don't want to take your plaquenil anymore. The worry is. the antacid will affect the absorption of the plaquenil and the amount your body can absorb. Plaquenil and heartburn rheumatoid. Plaquenil, a warning. lupus - reddit. PLAQUENIL Side Effects, Reviews by Patients -. Pills should only be split in half, not into smaller portions, such as thirds or quarters. The easiest pills to split are relatively flat round ones with a scored center, a slightly indented line that runs across the center of the pill. However, not every pill that has a scored center is meant to be split. So your doc isn’t doing to reintroduce the cellcept and he’s kind of throwing in the towel on the ulcers. Maybe he’s just giving the plaquenil more time. Anyway, that’s great that you caught a break on the neuropathy. I don’t think that it remits like that very often. You have half the battle won at least. Thanks for the info and best of luck. Splitting tablets in half is a practice that some patients, employers, healthcare providers, and even health insurance and managed care companies are now recommending. Tablet splitting under the direction of a healthcare provider can be safe and save you money, too.