Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Levaquin and hydroxychloroquine Scalp itching and plaquenil Antacid and plaquenil Hydroxychloroquine indications and contraindications Plaquenil Side Effects by Likelihood and Severity. these tend to have a Severe expression. A Disorder Of The Retina Of The Eye; Abnormal Function Of The Cornea In The Eye. Low Levels Of A. The causes of decreased kidney function fall into two categories, acute and chronic. A sudden decrease in kidney function, within hours to days, is called acute kidney injury or AKI. The causes of AKI can be broken down into prerenal, intrinsic and postrenal, depending on the source of the problem. This may cause protein to leak into the urine, along with red blood cells. Sometimes a kidney biopsy is needed to establish the exact diagnosis and treatment. Treatment options may include corticosteroids and immunosuppressive drugs to prevent loss of kidney function. This information was first printed in The Moisture Seekers, SSF's patient Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause decreased kidney function High Creatinine, Low Kidney Function And Low GFR, What Are the Causes of Decreased Kidney Function. Does plaquenil help with sleep For some, Sjogren's syndrome can and does indeed affect the kidneys, however Sjs is not the most frequent cause of kidney failure. The most common causes of kidney disease are diabetes and high blood pressure. People with a family history of any kind of kidney problem are also at risk for kidney disease. Reasonably Well Can Sjogren's Syndrome Cause Kidney Disease?. Sjögren’s & Kidney Disease. Plaquenil Hydroxychloroquine Sulfate - Sanofi. We provide a brief review of research on chronic kidney disease and cognitive performance, including dementia. We touch briefly on the literature relating end-stage-renal disease to cognitive function, but focus on studies of modest and moderate forms of chronic kidney disease CKD that precede dialysis and transplantation. I agree with Mariso, I doubt the Plaquenil is causing your low back pain. It's possible it's part of the disease. You shouldn't be on a dose no lower than 200mg and probably should be on 400 mg per day. If you can, I HIGHLY suggest you order the book The Lupus Encyclopedia by Dr Donald Thompson. Other causes of decreased kidney function leading to kidney failure are due to underlying disease and occur slowly over time. Prevention is the best chance to maintain kidney function, and controlling high blood pressure and diabetes over a lifetime can decrease the potential for progressive kidney damage.