Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. What is hydroxychloroquine used for Brazil nuts and plaquenil Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy. Chloroquine is metabolized in the liver, primarily by CYP2C8 and CYP3A4 enzymes, and it can selectively inhibit CYP2D6 activity. Drugs that inhibit CYP3A4 such as ritonavir may increase plasma levels of chloroquine. Potential interactions may also exist between chloroquine and drugs that are substrates for CYP2D6. 11,16,17 Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Facts on chloroquine Medicines for the Prevention of Malaria While Traveling., Chloroquine Information for Providers AIDSinfo Plaquenil zon Mar 16, 2020 Chloroquine is an immunosuppressive drug and anti-parasite commonly used in malaria treatment. It’s most often taken as a tablet by mouth. Is Chloroquine a Cure for Coronavirus? Scientists Say Maybe.. Hydroxychloroquine Uses, Dosage & Side Effects -. Teva-Chloroquine - Uses, Side Effects, Interactions -. Chloroquine may decrease the amount of ampicillin in your body and the ampicillin may not work as well. Certain vaccines rabies vaccine, cholera vaccine may not work as well if given while you. Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax, P. ovale, and P. falciparum, as well as certain parasitic worms and amoebas. Some mild side effects may occur, including headache and abdominal cramps, which are common to antimalarials. Chloroquine comes as a tablet, liquid, or injection. Your dose will depend on your medical condition, age, weight, and response to treatment. You can take this medicine with food if it causes an.