Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Hydroxychloroquine other uses Chloroquine and proguanil brand name Hydroxychloroquine overdose toxicokinetics and management The following case studies illustrate examples where Plaquenil administration was associated with either new onset psoriasis or flaring of pre-existing psoriasis. Case 1. A middle-aged woman sought another opinion for a puzzling rash which had been seen by two dermatologists. At first, skin biopsies showed features of eczema. Subsequent biopsies If you have psoriasis, chloroquine Aralen and hydroxychloroquine Plaquenil can cause problems. Other Medicines That Might Trigger a Flare A few other drugs to discuss with your doctor include Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Hydroxychloroquine side effects psoriasis What are the side effects of using hydroxychloroquine., Drugs & Medications That Can Trigger Psoriasis Flare-Ups Chloroquine diphsophateChloroquine phosphate molecular weightKeyhole chloroquine These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. It is known that antimalarial drugs that are helpful in LE are contraindicated in psoriasis 1. This old concept is supported by the recent study of Wolf et al. 11, who demonstrated that hydroxychloroquine induces hyperproliferation and irregular keratinization in cultured skin of psoriatic patients.