Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Immunosuppressant plaquenil Chloroquine pills given to troops in viet name Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. As part of rheumatoid arthritis treatment, your doctor will probably prescribe a nonsteroidal anti-inflammatory drug NSAID. These medications reduce pain and inflammation but do not slow down RA. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Ra treatments plaquenil Hydroxychloroquine Plaquenil - medications for., Plaquenil Uses, Dosage & Side Effects - Chloroquine combination therapy Many different drugs can be used as DMARDs in the treatment of RA, but some are used more often than others. DMARD Side Effects and Use Hydroxychloroquine Plaquenil and sulfasalazine. Treating Rheumatoid Arthritis With Disease-Modifying Drugs.. Rheumatoid Arthritis RA Treatment Medications, Surgery.. RA and Hydroxychloroquine How Effective is it for.. Disease-modifying antirheumatic drugs DMARDs. These drugs can slow the progression of rheumatoid arthritis and save the joints and other tissues from permanent damage. Common DMARDs include methotrexate Trexall, Otrexup, others, leflunomide Arava, hydroxychloroquine Plaquenil and sulfasalazine Azulfidine. Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild rheumatoid arthritis. They are not as powerful as other disease-modifying antirheumatic drugs, but they usually cause fewer side effects. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more.