Begin 1-2 days before travel, daily during travel, and for 7 days after leaving. Manufacturer Recommendations: 15 mg base (26.3 mg salt) orally once a day for 14 days Comments: -Recommended only for the radical cure of vivax malaria, the prevention of relapse in vivax malaria, or after the end of chloroquine phosphate suppressive therapy in vivax malaria-endemic area -Should be given with chloroquine phosphate (destroys erythrocytic parasites and stops attack) to destroy exoerythrocytic parasites Use: For the radical cure (prevention of relapse) of malaria due to Plasmodium vivax US CDC Recommendations: 30 mg base (52.6 mg salt) orally once a day for 14 days -Alternate regimen: 45 mg base (78.9 mg salt) orally once a week for 8 weeks Comments: -For the radical cure of malaria due to P vivax or P ovale -Since this drug usually is not active against asexual erythrocytic forms of plasmodia, it should be administered with other appropriate antimalarial agents. Can plaquenil make you tired Hydroxychloroquine rxlist Initially by mouth using tablets. For Child 14–17 years body-weight 45 kg and above. 310 mg once weekly, alternatively by mouth using syrup 300 mg once weekly, started 1 week before entering endemic area and continued for 4 weeks after leaving. Prophylaxis against Chloroquine-sensitive Plasmodium species Adult Dose The dosage for prophylaxis is 500 mg = 300 mg base administered once per week on exactly the same day of each week. Pediatric Dose The dosage for prophylaxis is 5 mg calculated as base, per kg of body weight, administered once per week on exactly the same day of each. The pharmacokinetics of chloroquine were studied in healthy volunteers who received one of three different multiple-dose regimens for 3 weeks once weekly 300 mg, twice weekly 200 mg and once daily 50 mg chloroquine. Plasma concentrations of chloroquine and metabolites were determined by h.p.l.c. with fluorescence detection. -The alternate regimen is recommended for patients with borderline glucose-6-phosphate dehydrogenase (G6PD) deficiency or as an alternative to the daily regimen. -This drug eradicates any hypnozoites that may be dormant in the liver and, thus, prevent relapses. Chloroquine po 300 mg daily prophylaxis Hydroxychloroquine Professional Patient Advice -, Chloroquine - FDA prescribing information, side effects and uses Hydroxychloroquine dermatology Each 500 mg tablet of Chloroquine phosphate contains the equivalent of 300 mg chloroquine base. In infants and children the dosage is preferably calculated by body weight. Prophylaxis against chloroquine-sensitive Plasmodium species Prophylaxis against chloroquine-sensitive Plasmodium species Adult Dose The dosage for prophylaxis is 500 mg. DailyMed - CHLOROQUINE PHOSPHATE tablet. The pharmacokinetics of three multiple dose regimens of chloroquine.. MALARIA, Prevention of Drug Adult dosage Pediatric dosage.. Mg 300 mg base PO at 24 hours & 48 hours after initial dose; Amebiasis, Extraintestinal. significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as. Infections should receive chloroquine prophylaxis 300 mg base po once a week during pregnancy. After delivery, patients with normal G6PD activity should be treated with primaquine or tafenoquine or continue with chloroquine prophylaxis for a total of 1 year. Primaquine can be used during breastfeeding if the infant is found Malaria prophylaxis is the preventive treatment of malaria. chloroquine 300 mg once weekly, and proguanil 200 mg once daily. Quinine sulfate 300 to 325 mg once daily this regimen is effective but not routinely used because of the unpleasant side effects of quinine.