It can decrease the pain and swelling of arthritis, prevent joint damage, and reduce the risk of long-term disability. You should not take it if you have a sulfa allergy. Sulfasalazine is used in the treatment of rheumatoid arthritis (RA), inflammatory bowel disease, and some other autoimmune conditions. Sulfasalazine comes in a 500mg tablet and should be taken with food and a full glass of water to avoid an upset stomach. Plaquenil antibiotic Chloroquin and ferroquine structure Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Jan 01, 2006 The Finnish Rheumatoid Arthritis Combination Therapy trial also provides data on the benefit of combination therapy in patients with early, clinically active RA 2 years. In an open-label trial, patients were randomized to triple therapy or sulfasalazine, with or without prednisolone, for 2 years. Rheumatoid arthritis RA is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. After the first week, the dose may be slowly increased to the usual dosage of two tablets (1g) twice a day. The medication is often started at low doses when treating RA to prevent side effects, typically one - two tablets a day. Azulfidine for rheumatoid arthritis vs plaquenil Methotrexate vs Sulfasalazine Comparison -, Combination Therapy for Rheumatoid Arthritis in the Era of. Hydroxychloroquine plaquenil for malaria protection Sulfasalazine Azulfidine is a drug prescribed for the treatment of mild to severe ulcerative colitis and the treatment of rheumatoid arthritis. Sulfasalazine Azulfidine has also been prescribed "off label" for Crohn's disease and ankylosing spondylitis. Azulfidine sulfasalazine Uses, Side Effects & Dosage. Osteoarthritis OA vs. Rheumatoid Arthritis RA.. Methotrexate, Plaquenil or Sulfasalazine Azulfidine.. Sulfasalazine Azulfidine® is used to treat ulcerative colitis, rheumatoid arthritis, and Crohn’s disease. Sulfasalazine Azulfidine® is part of a class of medicines called sulfa drugs. It’s a mix of salicylate, which is the main ingredient in aspirin, and an antibiotic. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. CONTRAINDICATIONS. Use of PLAQUENIL is contraindicated in patients with known hypersensitivity to 4 Sulfasalaine azulfidine, salazopyrin belongs to a class of drugs called sulfa drugs. It’s a combination of salicilate the main ingredient in aspirin and a sulfa antibiotic. Sulfasalazine works by slowing the radiographic progression damage to the joints of rheumatoid arthritis, and reducing pain and swelling.