Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine resistant malaria usmle Chloroquine and receptor mediated endocytosis I’m a 35/f and I’ve recently started orencia for seronegative RA after switching from MTX after 16 years. I’m wondering if anyone else on orencia is low key freaking out about COVID-19. I should mention that I also had thyroid cancer 4 years ago and work in a hospital surgical bookings so no patient contact. Cimetidine Moderate Avoid concomitant use of hydroxychloroquine and cimetidine as cimetidine may inhibit the metabolism of hydroxychloroquine as observed with the structurally similar chloroquine. However, the mechanism of inhibition of chloroquine metabolism appears to be via CYP inhibition, and hydroxychloroquine is not a known CYP substrate; cimetidine inhibition of hydroxychloroquine metabolism has not been demonstrated. Thyroid hormone levels can be altered by drugs at many levels including the hypothalamus, thyrotropes in the anterior pituitary gland, synthesis and secretion from the thyroid gland and metabolism of thyroid hormones through deiodination, sulfation and glucuronidation. Drugs may also affect thyroid hormone levels by altering affinity for or. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil and thyroid Things That Can Mess With Your Thyroid Medication - GoodRx, Plaquenil hydroxychloroquine sulfate dose, indications, adverse. Hydroxychloroquine sulfate monitoringPlaquenil and brain dizzinessWeight gain while using plaquenil Hypothyroidism in lupus can cause increased fatigue, cold intolerance, brain fog, dry skin, and weight gain. Symptoms of Graves’ disease the most common cause of hyperthyroidism, in which the immune system tricks the thyroid into making too much thyroid hormone include weight loss, tremors, heart palpitations. Thyroid therapy and lupus Lupus Foundation of America. DRUGS THAT SUPPRESS TSH OR CAUSE. - PubMed Central PMC. Lupus Symptoms Johns Hopkins Lupus Center. Rheumatoid arthritis is the most common autoimmune disorder coexisting with thyroid autoimmunity, about 3-4% of people with GD and HT also have rheumatoid arthritis and hydroxychloroquine is often prescribed. Sometimes, doctors prescribe Hydroxychloroquine Plaquenil for Hashimoto’s thyroiditis with positive results. PLAQUENIL® HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION PLAQUENIL h. ydroxychloroquine sulfate is a. white or practically white, crystalline. powder freely. soluble in water; practically insoluble in alcohol, chloroform, and in ether. The. chemical. name for. Plaquenil is currently in clinical trial relating to reducing thyroid antibodies, so I will update you all later on the findings. Please note, this drug does have a lot of potential side effects including irregular heartbeat, mental/mood changes anxiety, depression, hallucinations, shortness of breath, blurred vision, arm/leg/back pain, fatigue, and chest discomfort.