I was dx with Lupus in May, after being "treated" for idiopathic thrombocytopenia purpura for three and a half years. I was fortunate to have to switch hemotologists in April because my new Hemo did some additional tests which suggested Lupus. What must be evaluated while on hydroxychloroquine Hydroxychloroquine toxicity eye wiki Low white cells are a part of the autoimmune issue. This is something that I have dealt with for years. I have been on the Plaquenil a couple of years now and my immunologist told me that Plaquenil doesn't cause the same issues as the DMARDS or the methotrexates, imuran, etc. Low Blood Counts Due To Bone Marrow Failure; Low Blood Sugar; Low Levels Of A Type Of White Blood Cell Called Neutrophils; Low Levels Of White Blood Cells; Maculopathy; Mental Problems From Taking. White blood cell count increased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Methotrexate, and have Polyarthritis In any case, you could say that I was in denial for the first six months of my diagnosis. He referred me to a Rhuemy who ran some addition tests and asked me some questions to basically confirm the dx. Does plaquenil cause low wbc Plaquenil Uses, Dosage & Side Effects -, Common and Rare Side Effects for Hydroxychloroquine Oral Hydroxychloroquine for osteoarthritis My wbc is low also but my doctor just says it is because of my AI and he is watching it. It goes down each time I have my blood drawn although I take plaquenil. I need to find out what part of the count is low. I am not sick or get sick easily. Winnie Sjogrens Low WBC. Plaquenil and White blood cell count increased - eHealthMe. Common and Rare Side Effects for Cellcept Oral. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. A complete blood count CBC is the most commonly performed lab test in the U. S. and is used to analyze red blood cells RBCs, white blood cells WBCs, and platelets. Many people with systemic lupus have abnormal CBCs. White blood cell counts can be low leukopenia due to lupus, immunosuppressive therapy, or the presence of a virus. Does Plaquenil tablet reduce the count of white blood cells? I took Plaquenil for 8 month, I started in November 2017 with 400 mg two months then I started 200 mg for 5 months. The count of white cells was 5.7 in November and in January was 3.7 and in May become 2.5 the decrease of white cells due to the use of Plaquenil tablet My email is.