I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Hydroxychloroquine 200 mg tab mylan Side effects of taking plaquenil Hydroxychloroquine insomnia Hydroxychloroquine 200 mg does it make u gain weight Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking hydroxychloroquine without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking hydroxychloroquine. Well, so you DON'T have the aches later. Plaquenil slows the progression of the disease. Go ahead and call the Rhuemy now, or just wait until Monday, if you have had this for a few weeks anyway. I do love a drink every now and then but will love feeling better, even if a few months from now. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Stopping plaquenil cold turkey Ted's Remedies, Holistic Therapy Lupus Systemic Lupus Erythematosus, Hydroxychloroquine MedlinePlus Drug Information Plaquenil pharmaceutical companyChloroquine ineffective on exoAffects of stopping plaquenilHydroxychloroquine dose per kg I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Had to stop taking Plaquenil -. Can you quit plaquenil cold turkey, or have to wean. What is the correct way to discontinue use of plaquenil?. After a month and a half-and being very depressed-actually ready to jump out a window--no kidding--I stopped the plaquenil--cold turkey. The bad dreams stopped, I was sleeping again, still have some stomach problems. I don't know why--I go see the RA MD tomorrow and I am sure we will discuss this. I will not take plaquenil ever again. What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.